Radiological and laboratory features of infantile cortical hyperostosis

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[Infantile cortical hyperostosis].

The genetic aspects of infantile cortical hyperostosis are discussed. A pedigree is presented, based on the history and clinical and radiological investigations of all living members of the family, with data from 11 cases with the condition in two generations, and one possible case from a third generation. The data suggest that an autosomal dominant gene with varying expressivity could be respo...

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A case of infantile cortical hyperostosis.

Infantile cortical hyperosteosis (ICH) is usually a self-limited disease of infancy with bony changes, soft tissue swelling, fever, irritability, decreased appetite, and decreased movement of the affected bones. Its description in isolated patients or in multiple members of families suggests the existence of two different forms, namely a sporadic form and a familial form with incomplete penetra...

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Infantile cortical hyperostosis with raised immunoglobulins.

Two cases of infantile cortical hyperostosis are reported. Both had raised immunoglobulins. Particularly remarkable were the IgA and IgM levels, a finding infrequently reported.

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Ankylosing hyperostosis. I. Clinical and radiological features.

Ankylosing hyperostosis is a condition in which new bone is laid down on the right antero-lateral aspect of the dorsal vertebrae and across the intervertebral spaces forming spurs or bridges. The lumbar and cervical spines, pelvis, hips, and knees may also be involved. There is no single approved name for this condition. Oppenheimer (1942) described 'Calcification and ossification of vertebral ...

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Mineral balance in infantile cortical hyperostosis: effects of corticosteroids.

The effects on mineral metabolism of therapeutic doses of corticosteroids were investigated in infantile cortical hyperostosis; in four untreated cases the calcium, phosphorus, and magnesium balances were strongly positive. In one severe case, treatment with prednisolone was associated with an alteration to negative calcium and magnesium balance, and faecal losses of calcium were particularly h...

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ژورنال

عنوان ژورنال: International Orthopaedics

سال: 1998

ISSN: 0341-2695,1432-5195

DOI: 10.1007/s002640050258